A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2.
Dubois EL, Guitton-Sert L, Béliveau M, Parmar K, Chagraoui J, Vignard J, Pauty J, Caron MC, Coulombe Y, Buisson R, Jacquet K, Gamblin C, Gao Y, Laprise P, Lebel M, Sauvageau G, D d'Andrea A, Masson JY.
Dubois EL, et al.
Nucleic Acids Res. 2019 Aug 22;47(14):7532-7547. doi: 10.1093/nar/gkz514.
Nucleic Acids Res. 2019.
PMID: 31219578
Free PMC article.
A critical step in the activation of FA pathway is the monoubiquitination of FANCD2 and its binding partner FANCI. To better address the clinical phenotype associated with FANCI and the epistatic relationship with FANCD2, we created the first conditional inactivatio …
A critical step in the activation of FA pathway is the monoubiquitination of FANCD2 and its binding partner FANCI. To better address …